The recently enacted American Recovery and Reinvestment Act includes substantial funding for health and public health. Among other things, it provides $650 million to be spent on wellness and prevention activities, $500 million for health and public health manpower, and $1.1 billion for comparative effectiveness research. The challenge for policy makers is now to determine how to make the best use of these dollars. That is the topic of our discussion today with Dr. Jonathan Fielding and Dr. Michael McGinnis. Dr. Fielding is the Director of the Los Angeles County Department of Public Health and chairs the United States Task Force on Community Preventive Services, and he is also Chairman of the Board of Partnership for Prevention. Dr. McGinnis is a senior scholar at the Institute of Medicine and the founder of the Healthy People national health objectives movement.